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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA3
All Species:
42.73
Human Site:
Y356
Identified Species:
58.75
UniProt:
P30101
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30101
NP_005304.3
505
56782
Y356
L
E
R
F
L
Q
D
Y
F
D
G
N
L
K
R
Chimpanzee
Pan troglodytes
XP_001159528
485
54945
Y336
L
E
R
F
L
Q
D
Y
F
D
G
N
L
K
R
Rhesus Macaque
Macaca mulatta
XP_001108948
480
54081
Y331
L
E
R
F
L
Q
D
Y
F
D
G
N
L
K
R
Dog
Lupus familis
XP_535453
687
75990
Y538
L
E
R
F
L
Q
D
Y
F
D
G
N
L
K
R
Cat
Felis silvestris
Mouse
Mus musculus
P27773
505
56660
Y356
L
E
Q
F
L
Q
E
Y
F
D
G
N
L
K
R
Rat
Rattus norvegicus
P11598
505
56605
Y356
L
E
R
F
L
Q
E
Y
F
D
G
N
L
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517928
483
54617
Y333
L
E
R
F
L
Q
D
Y
F
D
G
N
L
K
K
Chicken
Gallus gallus
Q8JG64
505
56163
Y354
L
E
R
F
L
Q
D
Y
F
D
G
N
L
K
K
Frog
Xenopus laevis
NP_001080051
502
56103
Y353
L
E
R
F
L
Q
D
Y
F
D
G
K
L
K
R
Zebra Danio
Brachydanio rerio
NP_998070
488
54656
Y347
L
E
K
F
L
E
D
Y
F
A
K
R
L
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
F346
I
E
A
F
L
K
K
F
L
D
G
K
L
K
Q
Honey Bee
Apis mellifera
XP_623282
490
55838
A344
A
F
L
K
D
M
E
A
G
V
L
E
P
Y
L
Nematode Worm
Caenorhab. elegans
P34329
618
69779
I479
L
E
A
F
M
K
Q
I
S
S
G
K
A
K
A
Sea Urchin
Strong. purpuratus
XP_782981
472
51996
N335
A
F
I
Q
A
F
V
N
G
E
L
E
P
F
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
Y358
I
V
A
W
L
K
E
Y
F
D
G
K
L
T
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
F352
I
E
S
W
F
K
D
F
Q
D
G
K
V
A
V
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
F356
I
E
S
L
V
K
D
F
L
K
G
D
A
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
94.4
70.8
N.A.
93
92.2
N.A.
84.7
80.9
74.6
60
N.A.
32.6
49.5
36.7
50.5
Protein Similarity:
100
92.6
94.8
72.1
N.A.
97
96.2
N.A.
90.3
90.8
88.3
77.2
N.A.
53.4
63.7
50.4
65.9
P-Site Identity:
100
100
100
100
N.A.
86.6
93.3
N.A.
93.3
93.3
93.3
66.6
N.A.
46.6
0
33.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
93.3
80
N.A.
73.3
6.6
46.6
6.6
Percent
Protein Identity:
N.A.
34.3
N.A.
35.6
26.8
N.A.
Protein Similarity:
N.A.
51
N.A.
54.9
48.4
N.A.
P-Site Identity:
N.A.
40
N.A.
26.6
20
N.A.
P-Site Similarity:
N.A.
66.6
N.A.
60
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
18
0
6
0
0
6
0
6
0
0
12
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
6
0
59
0
0
71
0
6
0
0
0
% D
% Glu:
0
83
0
0
0
6
24
0
0
6
0
12
0
0
0
% E
% Phe:
0
12
0
71
6
6
0
18
65
0
0
0
0
6
0
% F
% Gly:
0
0
0
0
0
0
0
0
12
0
83
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
24
0
6
0
0
0
0
6
0
0
0
0
0
0
6
% I
% Lys:
0
0
6
6
0
30
6
0
0
6
6
30
0
71
12
% K
% Leu:
65
0
6
6
71
0
0
0
12
0
12
0
71
0
6
% L
% Met:
0
0
0
0
6
6
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
6
0
0
0
48
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
12
% P
% Gln:
0
0
6
6
0
53
6
0
6
0
0
0
0
0
6
% Q
% Arg:
0
0
48
0
0
0
0
0
0
0
0
6
0
0
48
% R
% Ser:
0
0
12
0
0
0
0
0
6
6
0
0
0
6
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% T
% Val:
0
6
0
0
6
0
6
0
0
6
0
0
6
0
6
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
0
0
0
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _